What is choline fenofibrate?
Choline fenofibrate is an antihyperlipedemic that is FDA approved for the treatment of primary hypercholesterolemia or mixed dyslipidemia and hypertriglyceridemia. Common adverse reactions include headache, back pain, nasopharyngitis, nausea, myalgia, diarrhea, and upper respiratory tract infection.
What is the difference between choline fenofibrate and fenofibrate?
[10] Choline fenofibrate is a newly developed choline salt of fenofibric acid and is more hydrophilic than fenofibrate. [11] Of the various fenofibrate formulations available, choline fenofibrate is the only formulation of fenofibrate which is approved by the US FDA for co-administration with statins.
What is fenofibrate acid used for?
Fenofibric acid is used together with a proper diet to treat high cholesterol and triglyceride (fat-like substances) levels in the blood. This may help prevent the development of pancreatitis (inflammation of the pancreas) caused by high levels of triglycerides in the blood.
What is the brand name for fenofibrate?
Fenofibrate is a prescription drug. It comes in two forms: oral tablet and oral capsule. The oral tablet is available as the brand-name drugs Fenoglide, Tricor, and Triglide. It’s also available as a generic drug.
How much fenofibric acid is in a choline capsule?
Each delayed release capsule contains choline fenofibrate, equivalent to 45 mg or 135 mg of fenofibric acid. The chemical name for choline fenofibrate is ethanaminium, 2hydroxy-N,N,N-trimethyl, 2- {4- (4-chlorobenzoyl)phenoxy] -2-methylpropanoate (1:1) with the following structural formula:
What are the side effects of choline fenofibrate?
Choline Fenofibrate is a choline formulation of fenofibrate, a synthetic phenoxy-isobutyric acid derivate and prodrug with antihyperlipidemic activity. H373 (98.04%): Causes damage to organs through prolonged or repeated exposure [ Warning Specific target organ toxicity, repeated exposure]
Which is the parent compound of choline fenofibrate?
Choline fenofibrate PubChem CID 11350701 Parent Compound CID 64929 (Fenofibric acid) Component Compounds CID 305 (Choline) CID 64929 (Fenofibric Date s Modify 2021-05-22 Create 2006-10-26
What’s the maximum dose of fenofibrate I can take?
The initial dose of fenofibric acid delayed-release capsules is 45 to 135 mg once daily. Dosage should be individualized according to patient response, and should be adjusted if necessary following repeat lipid determinations at 4 to 8 week intervals. The maximum dose is 135 mg once daily.