What is the best treatment for HER2 negative breast cancer?
Hormonal therapy is considered the standard initial treatment for HER2-negative metastatic breast cancer that is also hormone receptor-positive, and is often given in combination with targeted therapy. However, chemotherapy may also be given. A clinical trial may also be an option for treatment at any stage.
Can HER2-negative Be Cured?
When you have HER2-negative advanced (metastatic) breast cancer, treatment usually focuses on managing your disease, not curing the cancer. The goal is to help you live longer and have a better quality of life. This type of cancer is most often treated with systemic therapy.
Can HER2-negative become HER2-positive?
Research has shown that some breast cancers that are HER2-positive can become HER2-negative over time. Likewise, a HER2-negative breast cancer can become HER2-positive over time.
Is it better to be HER2-positive or negative?
HER2-positive cancer tends to be poorer in terms of prognosis than HER2-negative cancer because: It grows faster. It is more likely to spread to the lymph nodes fast. It is at least two times more likely to return than HER2-negative tumors.
What does it mean to have HER2 negative breast cancer?
When a breast cancer is HER2-negative, it means that the cancerous cells do not contain high levels of the protein HER2. There are many treatment options available for this type of breast cancer,…
What does a borderline HER2 test result mean?
An IHC 2+ test result is called borderline. If you have an IHC 2+ result, ask to have the tissue retested with the FISH test. Research has shown that some breast cancers that are HER2-positive can become HER2-negative over time.
What can I take for HER2 positive breast cancer?
In some cases, pertuzumab ( Perjeta) may be added in conjunction with Herceptin. This may be recommended for HER2-positive breast cancers at a higher risk of recurrence, like stage 2 and above, or for cancers that have spread to the lymph nodes.
What does HER2 stand for in medical category?
HER2 stands for human epidermal growth factor receptor 2. HER2 proteins are found on the surface of breast cells. They’re involved in normal cell growth but can become “overexpressed.” This means that levels of the protein are higher than normal.