What happens when the caudate nucleus is damaged?
Reports of human patients with selective damage to the caudate nucleus show unilateral caudate damage resulting in loss of drive, obsessive-compulsive disorder, stimulus-bound perseverative behavior, and hyperactivity.
What are the disorders of caudate nucleus?
[3] Research has implicated caudate nucleus dysfunction in several pathologies, including Huntington and Parkinson disease, various forms of dementia, ADHD, bipolar disorder, obsessive-compulsive disorder, and schizophrenia.
What is a caudate lesion?
Caudate vascular lesions with concomitant neighboring structure involvement represent a specific stroke syndrome, usually caused by small-artery disease and in one fifth of the patients caused by cardiac embolism.
What is a caudate stroke?
Caudate strokes may present with isolated cognitive and language dysfunction. Though part of the basal ganglia, isolated lesions of the caudate can present with cognitive and language problems rather than movement abnormalities.
What are the long-term effects of a caudate stroke?
Studies of patients with caudate strokes have suggested that unilateral or bilateral damage may result in significant memory impairment, mood change, or a frontal behavioral syndrome. 89101112 There are few studies, however, of patients with unilateral caudate lesions that have examined long-term outcome of memory and mood disorders.
Are there any disorders associated with the caudate nucleus?
Dysfunction in the caudate has also been linked to a number of other conditions, such as obsessive-compulsive disorder and attention-deficit hyperactivity disorder. But the caudate’s potential contribution to those disorders is still being investigated, as is the full extent of the cognitive functions of the caudate in general.
How many patients are diagnosed with caudate ischemic stroke?
Patients with caudate stroke were 1% of our registry, which included 3050 patients (total, 2450 ischemic stroke and 600 hemorrhagic stroke). CT and MRI were performed in all patients with caudate ischemic stroke and read by investigators blinded to neurological and neuropsychological findings in each patient.
How are acute caudate vascular lesions studied in stroke?
Methods —We studied all patients with acute caudate stroke confirmed by CT or MRI who were admitted to our stroke unit over a 5-year period. A database containing risk factors, clinical features, type and mechanism of stroke, and caudate vascular territories was analyzed.
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