How are dispersible tablets made?

How are dispersible tablets made?

Cotton candy process: By this method matrix of polysaccharides are prepared by simultaneous action of rapid melting and spinning. This candy floss matrix is then recrystalized milled and mixed with active drug along with excipients and compressed to form a fast dissolving tablet[30].

What is dispersible tablet?

A dispersible tablet is a tablet that disintegrates in water or other liquid. These dispersible tablets disintegrate quickly in water or disperse immediately in the mouth. Aspirin is available as a dispersible tablet that you can dissolve in water before taking.

What is the disintegration time for dispersible tablet?

Dispersible tablets disintegrate within 3 minutes when examined by 5.3 Disintegration test for tablets and capsules, but using water R at 15–25° C.

How is quality by design used in dispersible tablets?

The focus of the current investigations was to apply quality by design (QbD) approach to the development of dispersible tablets. Critical material and process parameters are linked to the critical quality attributes of the product. Variability is reduced by product and process understanding which tr …

What are oral dispersible tablets and what are they used for?

Oral dispersible tablets (ODTs) are patient friendly dosage form that rapidly disintegrate or dispersed in mouth without the need of water.

Why are flavoring agents added to dispersible tablets?

These are the organoleptic additives used to enhance the elegance and aesthetic appearance of the formulation. The solid dosage forms such as conventional tablets, dispersible tablets, and fast dissolving tablets require organoleptic ingredients to be added to the formulation. Flavoring agents are added to:

Is there bioequivalence between dispersible tablets and zonisamide?

The bioequivalence of oral dispersible tablets of zonisamide 100 and 300 mg and immediate-release reference capsules has been assessed in two open, randomized-sequence, single-dose, 2-period, 2-treatment, crossover studies; the test formulation met regulatory criteria for bioequivalence [ 66 ].