What is spironolactone 25mg used for?
Spironolactone is used to treat certain patients with hyperaldosteronism (the body produces too much aldosterone, a naturally occurring hormone); low potassium levels; heart failure; and in patients with edema (fluid retention) caused by various conditions, including liver, or kidney disease.
What does spironolactone do for the heart?
Based on the pathophysiology of resistant hypertension, spironolactone use in patients with heart failure with preserved ejection fraction (HFpEF) with resistant hypertension, in addition to lowering blood pressure, may reduce the risk of volume overload, resulting in a reduced risk of heart failure and cardiovascular …
What is spironolactone mg used for?
Spironolactone is used to treat high blood pressure and heart failure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems.
Why is spironolactone bad for you?
Spironolactone can cause a drop in blood pressure when going from sitting to standing (postural hypotension) which causes dizziness, a light headed feeling or fainting. Uncommon side effects include drowsiness, fatigue, headache, loss of libido (sex drive) and very rarely, confusion and loss of co- ordination.
What is the formula for spironolactone 25MG tablets?
Spironolactone tablets, USP contain 25 mg, 50 mg, or 100 mg of the aldosterone antagonist spironolactone, 17-hydroxy-7α-mercapto-3-oxo-17α-pregn-4-ene-21-carboxylic acid γ-lactone acetate, which has the following structural formula:
What are the side effects of oral spironolactone tablets?
Mild side effects* of spironolactone oral tablets can include: 1 nausea and vomiting 2 diarrhea 3 belly cramps 4 leg cramps 5 dizziness 6 drowsiness 7 headache 8 confusion 9 menstrual problems, such as irregular periods or bleeding that happens after menopause 10 sexual problems, such as reduced sex drive or erectile dysfunction
When to discontinue spironolactone due to side effects?
More frequent monitoring may be needed when Spironolactone is given with other drugs that cause hyperkalemia or in patients with impaired renal function. If hyperkalemia occurs, decrease the dose or discontinue Spironolactone and treat hyperkalemia.
How is spironolactone used to treat heart failure?
Spironolactone is used to treat heart failure, high blood pressure (hypertension), or hypokalemia ( low potassium levels in the blood). Spironolactone also treats fluid retention (edema) in people with congestive heart failure, cirrhosis of the liver, or a kidney disorder called nephrotic syndrome. Spironolactone is also used to diagnose