Does myeloma cause avascular necrosis?
Conclusion: AVN is a rare and usually asymptomatic complication during myeloma therapy. Cumulative dexamethasone dose, male sex, and younger age, but not thalidomide, increase the risk of AVN.
What causes avascular necrosis of femoral head?
These causes include fractures, dislocations, chronic steroid use, chronic alcohol use, coagulopathy, congenital causes; among many others. Avascular necrosis of the femoral head is a debilitating disease and is an important condition requiring healthcare professionals to be vigilant for its presentation.
What is avascular necrosis of femur?
Avascular necrosis is the death of bone tissue due to a lack of blood supply. Also called osteonecrosis, it can lead to tiny breaks in the bone and the bone’s eventual collapse. A broken bone or dislocated joint can interrupt the blood flow to a section of bone.
What are the stages of AVN?
What is the Steinberg Classification System for femoral head avascular necrosis (AVN)?
- Stage I – Normal radiographs; abnormal MRI or bone scan.
- Stage II – Abnormal lucency or sclerotic site in femoral head.
- Stage III – Subchondral collapse (ie, crescent sign) without flattening of femoral head.
What are the symptoms of multiple myeloma in the femur?
On the whole body blood pool images increased perfusion at the proximal left femur was seen. Delayed whole body images demonstrate multiple focal intensities of tracer involving the medial end of the left clavicle as well as the 2nd and 5th ribs anteriorly.
Is bone avascular?
Avascular necrosis is the death of bone tissue due to a lack of blood supply. Also called osteonecrosis , it can lead to tiny breaks in the bone and the bone’s eventual collapse. A broken bone or dislocated joint can interrupt the blood flow to a section of bone.
What is the uptake of blood in a femur fracture?
The distribution of uptake does not fit a usual pattern for neck of femur fracture. Physiological bladder and pudendal uptake is noted. On the whole body blood pool images increased perfusion at the proximal left femur was seen.
Is there a bone scan for multiple myeloma?
A: Not really. Both myeloma and skeletal metastases can have increased activity. A normal bone scan despite extensive radiographic abnormality would favour multiple myeloma. A: Fractures. Loading images… There is a lytic expansile mass in the intertrochanteric region of the left femur measuring 3.6 x 4.6 x 3.4 cm.