Can a dog overdose on theophylline?

Can a dog overdose on theophylline?

Severe toxic effects can occur but are rare. These signs include seizures and collapse and may indicate that the dose of theophylline is too high. Contact your veterinarian immediately if you observe these side effects in your pet.

What is aminophylline toxicity?

Aminophylline or theophylline overdose occurs when someone takes more than the normal or recommended amount of these medicines. This can be by accident or on purpose. This article is for information only. DO NOT use it to treat or manage an actual overdose.

What is the most common symptom of theophylline toxicity?

Consequences of theophylline intoxication include metabolic disturbances (hypokalemia, hyperglycemia, and metabolic acidosis), nausea, vomiting, and, in severe cases, seizures, cardiac arrhythmias, and death.

What are the signs and symptoms of theophylline toxicity?

Neurological signs include tremors (most common), restlessness, agitation, and altered mental status. Persistent seizures may occur with serum levels > 25 mcg/mL. Gastrointestinal manifestions are nausea, vomiting, abdominal cramps, and diarrhea.

What are the side effects of aminophylline for dogs?

A dog on aminophylline can experience side effects such as vomiting, diarrhea, anxiety or nervousness, insomnia, or increased hunger, thirst and urination. Side effects may subside with continued therapy or may require dosage adjustments. Precautions: Caution should be used when giving aminophylline to dogs with seizure disorders.

Are there any side effects to theophylline for dogs?

Severe toxic effects can occur but are rare. These signs include seizures and collapse and may indicate that the dose of theophylline is too high. Contact your veterinarian immediately if you observe these side effects in your pet.

How are fluoroquinolones and theophylline related in dogs?

The absorption of oral fluoroquinolones is markedly impaired by drugs that contain divalent or trivalent cations, such as: In humans and dogs, fluoroquinolones inhibit the CYP1A2 metabolism of theophylline. This has lead to theophylline toxicity in humans.

How often should I give my Dog aminophylline?

In addition, aminophylline is also available as 250 mg and 500 mg suppositories. Medication should never be administered without first consulting your veterinarian. In dogs, aminophylline is dosed at 3 to 5 mg per pound (6 to 11 mg/kg) orally, or by injection, every 8 hours.

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